Her emotions are now centered on Casaubon's young cousin Ladislaw but her husband becomes furiously jealous of this friendship. A hurried marriage and honeymoon in Rome follow, during which Dorothea is rapidly disillusioned by Casaubon's cold and emotionless personality. However, her life takes an unexpected twist when she meets the older, scholarly Edward Casaubon, an equally wealthy clergyman who has undertaken to write an important thesis on mythology.

She is well-off, good-looking and engaged to be married to a wealthy neighbor, Sir James Chettam. Dorothea Brooke is a gentle and idealistic young woman who seeks a noble cause that she can dedicate her life to. Set in the fictitious Midlands town of Middlemarch, the plot contains three main themes which are connected through a complex maze of relationships and devices. Women's status, the industrial revolution, the disappearance of rural England and the rise of the newly rich and brash middle class, politics, sexual mores, morality, religion and marriage were some of the many viewpoints explored in this very significant work. Planned and executed on an epic scale, it is a monumental work that brings together many streams, plot ideas, characters, social and economic concepts and the author's deep concern for the issues of the day. In 1874, it was finally compiled into a full length novel and attained instant fame and success. Middlemarch: A Study of Provincial Life first appeared as an eight-part serial novel in 1871-72.

Meanwhile, personal problems intervened and when she took up the project again, it was with a renewed sense of creativity. George Eliot's seventh and perhaps most famous novel almost didn't get written! It took birth as a short novella titled Miss Brooke but she was unhappy with its progress and finally in despair, she decided to put it aside for a couple of years.

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